by uesday, February 3, 2026
19:00 (19:00) Forge FC vs. Tigres UANL – Hamilton Stadium, Hamilton, CAN
21:00 (20:00) Club Olimpia Deportivo vs. Club América – Estadio Chelato Uclés, Tegucigalpa, HON
23:00 (20:00) San Diego FC vs. Pumas UNAM – Snapdragon Stadium, San Diego, USA
Wednesday, February 4, 2026
20:00 (19:00) CSD Xelajú MC vs. CF Monterrey – Estadio Cementos Progreso, Ciudad de Guatemala, GUA
22:00 (19:00) Vancouver FC vs. Cruz Azul – Willoughby Stadium, Langley, CAN
Tuesday, February 17, 2026
20:00 (20:00) Atlético Ottawa vs. Nashville SC – Hamilton Stadium, Hamilton, CAN
22:00 (21:00) Real CD España vs. Los Angeles FC – Estadio Francisco Morazán, San Pedro Sula, HON
Wednesday, February 18, 2026
18:00 (19:00) Defence Force FC vs. Philadelphia Union – Hasely Crawford Stadium, Port of Spain, TRI
20:00 (21:00) O&M FC vs. FC Cincinnati – Estadio Cibao FC, Santiago de los Caballeros, DOM
22:00 (21:00) CS Cartaginés vs. Vancouver Whitecaps FC – Estadio Fello Meza, Cartago, CRC
Thursday, February 19, 2026
20:00 (20:00) Sporting San Miguelito vs. LA Galaxy – Estadio Universitario, Penonomé, PAN
Round One Second Leg Matches
*Eastern Time (Local Time) and home team listed first
Tuesday, February 10, 2026
20:00 (19:00) Pumas UNAM vs. San Diego FC – Estadio Olímpico Universitario, Ciudad de México, MEX
22:00 (21:00) Tigres UANL vs. Forge FC – Estadio Universitario, Monterrey, MEX
Wednesday, February 11, 2026
20:00 (19:00) Club América vs. Club Olimpia Deportivo – Estadio Ciudad de los Deportes, Ciudad de México, MEX
22:00 (21:00) CF Monterrey vs. CSD Xelajú MC – Estadio BBVA, Monterrey, MEX
Thursday, February 12, 2026
20:00 (19:00) Cruz Azul vs. Vancouver FC – Estadio Cuauhtémoc, Puebla, MEX
Tuesday, February 24, 2026
20:00 (19:00) Nashville SC vs. Atlético Ottawa – GEODIS Park, Nashville, USA
22:00 (19:00) Los Angeles FC vs. Real CD España – BMO Stadium, Los Angeles, USA
Wednesday, February 25, 2026
19:00 (19:00) FC Cincinnati vs. O&M FC – TQL Stadium, Cincinnati, USA
21:30 (18:30) Vancouver Whitecaps FC vs. CS Cartaginés – BC Place, Vancouver, CAN
23:30 (20:30) LA Galaxy vs. Sporting San Miguelito – Dignity Health Sports Park, Carson, USA
Thursday, February 26, 2026
19:00 (19:00) Philadelphia Union vs. Defence Force FC – Subaru Park, Philadelphia, USA
Round of 16 First Leg Matches
*Eastern Time (Local Time) and home team listed first
Tuesday, March 10, 2026
TBC (TBC) Winner R1 Matchup 8 vs. Winner R1 Matchup 7
TBC (TBC) Winner R1 Matchup 4 vs. Winner R1 Matchup 3
TBC (TBC) Winner R1 Matchup 5 vs. LD Alajuelense
Wednesday, March 11, 2026
TBC (TBC) Winner R1 Matchup 6 vs. Inter Miami CF
TBC (TBC) Winner R1 Matchup 1 vs. Deportivo Toluca FC
TBC (TBC) Winner R1 Matchup 2 vs. Mount Pleasant FA
Thursday, March 12, 2026
TBC (TBC) Winner R1 Matchup 10 vs. Winner R1 Matchup 9
TBC (TBC) Winner R1 Matchup 11 vs. Seattle Sounders FC
Round of 16 Second Leg Matches
*Eastern Time (Local Time) and home team listed first
Tuesday, March 17, 2026
21:00 (19:00) LD Alajuelense vs. Winner R1 Matchup 5 – Estadio Alejandro Morera Soto, Alajuela, CRC
TBC (TBC) Winner R1 Matchup 3 vs. Winner R1 Matchup 4
Wednesday, March 18, 2026
19:00 (19:00) Inter Miami CF vs. Winner R1 Matchup 6 – Inter Miami CF Stadium, Fort Lauderdale, USA
TBC (TBC) Winner R1 Matchup 7 vs. Winner R1 Matchup 8
23:00 (21:00) Deportivo Toluca FC vs. Winner R1 Matchup 1 – Estadio Nemesio Díez, Toluca, MEX
23:00 (20:00) Seattle Sounders FC vs. Winner R1 Matchup 11 – TBC
Thursday, March 19, 2026
19:00 (18:00) Mount Pleasant FA vs. Winner R1 Matchup 2 – National Stadium, Kingston, JAM
TBC (TBC) Winner R1 Matchup 9
